禁忌、迷思、慾望、恐懼

疾病的迷思隨處可見，不過以性病的迷思最為嚴重，社會大眾也因為迷思而經常對性病病患輕蔑嘲諷。 

菜花會好 但是病毒一輩子都會在 抵抗力差的話會再復發.... 

 好慘 這是不會好的 而且就算帶套也還是會傳染給別人

菜花病毒超級可怕，雖然死不了，但終生都要得電燒

 先別說AIDS 如果是菜花也是無法根治的 還會傳染給小孩

菜農也是一輩子的農夫喔....雖然說不會死啦

上述推文是取自PTT鄉民的推文， 關於菜花，上述推文的說法屢見不鮮，然而事實真的是那樣嗎？

 

先定義根治的意義，根治是指身體完全沒有菜花病毒，自然也無從復發；要驗有無菜花病毒，可使用HPV DNA測試，如果刷遍私處可能感染菜花的上皮，包刮陰囊、陰唇、陰莖、陰蒂等處上皮，而HPV DNA都是陰性，即代表沒有任何菜花病毒，也就是所謂的根治，而研究調查也是以HPV DNA測試來決定HPV的有無。

 

接著看以下專業的說法。

Science 2000 Dec 1;290(5497):1651.
http://www.sciencemag.org/cgi/content/full/290/5497/1651a
"Screening for Cervical Cancer"

The majority of HPV-infected women will spontaneously clear their infections over time.
大多數的HPV感染會隨著時間過去而被清除掉。

 

Science 2005 Apr 29;308(5722):619.
http://www.sciencemag.org/cgi/content/full/308/5722/619
"HPV's Peculiarities, From Infection to Disease"

If the virus dodges the initial immune response and wangles its way into the epithelium, immune cells that specifically eliminate infected cells, combined with a continued antibody assault, typically clear the infection.
如果HPV侵入，宿主會啟動免疫反應排除遭感染的細胞，加上抗體協助，大都能清除感染。

 

The New England Journal of Medicine 2001 May 24;344(21):1603-7
http://content.nejm.org/cgi/content/full/344/21/1603
"Current Approaches to Cervical-Cancer Screening"

Most infections clear within 24 months.
大多數人會在兩年內清除掉HPV。

 

The New England Journal of Medicine 1998 Feb 12;338(7):423-8
http://content.nejm.org/cgi/content/full/338/7/423
"Natural History of Cervicovaginal Papillomavirus Infection in Young Women"

The median duration of HPV infection was 8 months (95 percent confidence interval, 7 to 10). By 12 months after the incident infection, 70 percent of the women were no longer infected, and by 24 months only 9 percent continued to be infected.
HPV感染時間大約持續8個月，過了一年有70%女人清除HPV，過了兩年有91%女人清除HPV。

 

The New England Journal of Medicine 2003 Feb 6;348(6):489-90
http://content.nejm.org/cgi/content/full/348/6/489
"Adding a Test for Human Papillomavirus DNA to Cervical-Cancer Screening"

These tens of millions of infections are usually transient and clinically nonsignificant, although they frequently produce temporary cytologic changes. Fortunately, few HPV-infected women actually become persistently infected (for example, approximately 10 percent remain infected at five years).
HPV短暫感染的案例不計其數，僅有10%的案例會發展成持續感染。

 

The New England Journal of Medicine 2007 Oct 18;357(16):1589-97
http://content.nejm.org/cgi/content/full/357/16/1589
"Human Papillomavirus and Papanicolaou Tests to Screen for Cervical Cancer"

The infection is usually transient.
HPV感染通常是短暫的。

 

The Journal of the American Medical Association 2007 Feb 28;297(8):813-9
http://jama.ama-assn.org/cgi/content/full/297/8/813
"Prevalence of HPV Infection Among Females in the United States"

Although HPV infection is common, studies suggest approximately 90% of infections clear within 2 years.
HPV感染非常常見，90%案例會在兩年內清除感染。

 

The Journal of the American Medical Association 2007 Jul 4;298(1):38
http://jama.ama-assn.org/cgi/content/full/298/1/38-a
"HPV Prevalence and Transmission—Reply"

Most HPV infections will clear and only a small fraction of infections persist.
大多數HPV感染會被清除掉，只有小部分會變成持續性感染。

 

Nature Reviews Cancer 2007 Jan;7(1):11-22
http://www.nature.com/nrc/journal/v7/n1/full/nrc2050.html
"The Natural History of Cervical HPV infection: Unresolved Issues"

HPV infections are usually transient.
HPV感染通常是短暫的。

 

The Lancet 2007 Sep 8;370(9590):890-907
http://0rz.tw/294fn
"Human Papillomavirus and Cervical Cancer"

Most HPV infections clear within 2 years
大多數HPV感染會在兩年內清除掉。

 

有點醫學程度的人，都知道上面幾個Journal的威力，但是美中不足的是這些統計並不單純統計引起菜花的HPV 6 和HPV 11，不過即使是高風險的HPV 16和HPV 18感染案例，絕大部分的人也都能清除掉，只是比率有可能不會到9成那麼高，特別是HPV 16。

 

連高風險型的HPV尚且如此，何況菜花病毒是HPV中的肉腳！

 

儘管實際上菜花病毒真的是HPV中的肉腳，但還是必須引用證據才算數，以下就引用一篇調查。雖然說以下引用paper的Journal點數不如上述10篇那樣權威，但至少在該領域還算是滿前面的。

Cancer Epidemiology Biomarkers & Prevention 16, 709-715, April 1, 2007
http://cebp.aacrjournals.org/cgi/content/full/16/4/709

圖個方便，直接看下表。

 

就算HPV 6 DNA兩年後陰性比率沒有100%，98.3%也夠高了，足以否定掉菜花不治論。

 

假如覺得paper的話很不中聽，沒關係，還有下一篇專業醫師的說法。